1 Updates

Voila! Ageing can be reversed, say scientists

Dec 19 2013, 11:24pm CST | by

Sydney, Dec 20 (IANS) The ageing process is like the married couple next door -- when young, they communicate well, but over many years the communication breaks down.

Sydney, Dec 20 — The ageing process is like the married couple next door -- when young, they communicate well, but over many years the communication breaks down. And as in relationships, says a new...

Filed under: news

Full Story below YouTube Videos

 
 

 

17 weeks ago

Voila! Ageing can be reversed, say scientists

Dec 19 2013, 11:24pm CST | by

Sydney, Dec 20 (IANS) The ageing process is like the married couple next door -- when young, they communicate well, but over many years the communication breaks down.

Sydney, Dec 20 — The ageing process is like the married couple next door -- when young, they communicate well, but over many years the communication breaks down.

And as in relationships, says a new study, restoring communications reverses the ageing process, at least in mammals.

A series of molecular events in our body enable communication inside cells between the nucleus and mitochondria, also called "cell's powerhouse".

As communication breaks down, ageing accelerates. By administering a molecule naturally produced by the human body, scientists restored the communication network in older mice.

"Subsequent tissue samples showed key biological hallmarks that were comparable to those of much younger animals," said David Sinclair, senior author on the study and Harvard Medical School Professor of Genetics.

Mitochondria generate chemical energy to carry out essential biological functions. As these self-contained organelles become increasingly dysfunctional over time, many age-related conditions such as Alzheimer's disease and diabetes occur.

Sinclair and his team primarily focused on a group of genes called sirtuins. Previous studies from his lab showed that one of these genes, SIRT1, was activated by the compound resveratrol, which is found in grapes, red wine and certain nuts.

They studied mice in which this SIRT1 gene had been removed. While they accurately predicted that these mice would show signs of ageing, including mitochondrial dysfunction, they were surprised to find that most mitochondrial proteins coming from the cell's nucleus were at normal levels.

Cells stay healthy as long as coordination between the genomes remains fluid. SIRT1's role is that of an intermediary, akin to a security guard, said Sinclair.

"There's clearly much more work to be done here, but if these results stand, then many aspects of ageing may be reversible if caught early," said Sinclair.

This study was a joint project between Harvard Medical School, the National Institute on Ageing, and the University of New South Wales, Sydney.

The findings of the study have been published in the latest edition of the journal Cell.

IANS

Source: IANS

 

Don't miss ...

 

<a href="/latest_stories/all/all/27" rel="author">IANS</a>
The Indo-Asian News Service (IANS) was established in 1986, initially to serve as an information bridge between India and its thriving diaspora in North America. Today it is a full-fledged, 24 by 7 agencies putting out the real-time news from India, South Asia and news of interest to this region around the world.

 

blog comments powered by Disqus

Latest stories

Microsoft Results Beat Estimates, Cheer Investors
The bad news for Microsoft in its fiscal-third quarter was that sales and earnings were both off from a year ago. But the company beat Wall Street estimates and showed surprising strength in its Windows business. Shares...
 
 
Google, Apple settle high-tech workers' lawsuit
SAN FRANCISCO (AP) — Google, Apple, Intel and Adobe Systems have settled a class-action lawsuit alleging they conspired to prevent their engineers and other highly sought technology workers from getting better job...
 
 
GameStop Dramatically Rolling Back Games Business
“Game” may be right there in the name, but brick and mortar video game store GameStop is looking to diversify. CEO Paul Raines told investors that the company plans on making an aggressive expansion into “gaming...
 
 
Apple: Rotting From The Core?
Apple released results on April 23: The company announced higher dividends, increasing stock buybacks from $60 billion to $90 billion, a 7 for 1 stock split, and higher earnings. The stock shot upward by $44 per share...
 
 
 

Latest from the Network

Google, Apple settle high-tech workers' lawsuit
SAN FRANCISCO (AP) — Google, Apple, Intel and Adobe Systems have settled a class-action lawsuit alleging they conspired to prevent their engineers and other highly sought technology workers from getting better job...
Read more on Business Balla
 
Microsoft Results Beat Estimates, Cheer Investors
The bad news for Microsoft in its fiscal-third quarter was that sales and earnings were both off from a year ago. But the company beat Wall Street estimates and showed surprising strength in its Windows business. Shares...
Read more on Apple Balla
 
Google, Apple settle high-tech workers' lawsuit
SAN FRANCISCO (AP) — Google, Apple, Intel and Adobe Systems have settled a class-action lawsuit alleging they conspired to prevent their engineers and other highly sought technology workers from getting better job...
Read more on Apple Balla
 
Oregon moves to dump health exchange website
PORTLAND, Ore. (AP) — Oregon, once expected to be a national leader in the federal health care overhaul, on Thursday moved to become the first state to dump its troubled online health exchange and use the federal...
Read more on Business Balla
 
Cloud strength helps Microsoft earnings top Street
LOS ANGELES (AP) — In Satya Nadella's first quarterly earnings release as chief executive, Microsoft Corp. on Thursday posted earnings and revenue that beat Wall Street expectations, offering new justification for the...
Read more on Business Balla
 
Aaron Carter wants to 'sweep' Hilary Duff off feet
Aaron Carter wants to "sweep" Hilary Duff "off her feet". The former pop star dated the 26-year-old singer-and-actress for 18 months when they were teenagers, but he now wants the chance to rekindle their romance....
Read more on Celebrity Balla
 
Amazon Shares Rise As Sales Growth Remains Strong
A big question for shareholders of Amazon.com was the strength of its sales growth for the first quarter. The answer today was sales growth is still darn strong, and shares were higher after hours. Amazon.com said it...
Read more on Business Balla
 
Visa Shares Falling On Light Revenue Despite 26% Jump In Second Quarter Profit
Visa, the world’s largest credit and debit card company, reported a 26% jump in second quarter fiscal 2014 profit Thursday afternoon, but shares of the payment technology company are down in after-hours trading thanks...
Read more on Business Balla
 
Do The FDA's Proposed E-Cigarette Restrictions Go Far Enough?
Today the Food and Drug Administration (FDA) finally announced proposed regulations for e-cigarettes, responding to pressure from public health advocates. The popular battery-powered vaporizing devices have come under...
Read more on Business Balla
 
Africa's Richest Woman Plans To Increase Stake in Unitel
Africa’s richest woman, Isabel dos Santos, plans to increase her stake in Unitel, Angola’s largest mobile phone company. According to a report by Portuguese newspaper, Publico, dos Santos (who already owns 25% of Unitel...
Read more on Business Balla
 
 
Auto Balla Sexy Balla Sport Balla TV Balla Politics Balla Movie Balla Apple Balla Business Balla Ad Balla Celebrity Balla