360° Coverage : Human gut microbes may help fight obesity: Study

Human gut microbes may help fight obesity: Study

Washington, Sep 6 (IANS) Lab mice receiving gut bacteria from obese humans are likely to put on more weight compared to those given bacteria from the gut of lean humans, US researchers say.

Sep 6 2013, 4:16am CDT | by IANS

Human gut microbes may help fight obesity: Study
Photo Credit: -, Getty Images

Washington, Sep 6 — Lab mice receiving gut bacteria from obese humans are likely to put on more weight compared to those given bacteria from the gut of lean humans, US researchers say.

The findings demonstrate the transmission of the physical and metabolic traits via gut microbes and represent an important step towards developing anti-obesity treatment with bacteria, Xinhua reported, citing the Science journal.

Researchers from the Washington University recruited four human twin pairs - two obsese and two lean - and transferred the gut microbiota from each of them into the guts of germ-free mice that had been raised under sterile conditions.

They found that the recipients of the obese twins' microbiota gained more fat than the recipients of the lean twins' microbiota when the mice were fed a standard diet.

"This wasn't attributed to the differences in the amount of food they consumed, so there was something in the microbiota that transmitted this trait. Our question became: What were the components responsible," said Jeffrey Gordon, director for the Centre of Genome Sciences and Systems Biology at Washington University.

Analysis of the bacteria showed that bacteroidetes phylum could pass from the lean mice and colonise the obese mice, suggesting that these were largely responsible for protection against weight gain.

According to the researchers, none of the bacteria from the obese mice could invade the lean mice to make them accumulate fat.

To learn more, the researchers formulated diets for the mice that were representative of modern Western diets - low in fibre and high in saturated fats - and found both the obese and lean mice appeared to be unaffected by the others' gut microbes.

However, when the animals were given the "healthier", high-fibre and low-fat human diet, the results were the same as before.

The findings indicated that more complex interactions between diet, body mass and gut microbiota underlie human metabolic disturbances than researchers have appreciated.

IANS

Source: IANS

 
 
 

blog comments powered by Disqus

Latest stories

Apple Pay has successful Black Friday
Apple Pay has successful Black Friday
Payment system gearing up for Christmas
 
 
Apple to stop iPhone 5C production
Apple to stop iPhone 5C production
Middle of 2015 is target date
 
 
Apple tops Android on Black Friday
Apple tops Android on Black Friday
iOS accounts for more online mobile sales
 
 
All Cyber Monday Sales
All Cyber Monday Sales
Cyber Monday 2014 is here and all sales and deals are available now. Find below the best Cyber Monday Sales events.
 
 
 

Latest from the Network

Australian researcher discovers first artwork by early human
Sydney, Dec 4 (IANS) An Australian researcher has discovered what is believed to be the first artwork created by a human. The simple zigzag pattern found on a fossilized shell from the Indonesian island of Java has...
Read more on Celebrity Balla
 
Insects compete with rats to clear garbage
New York, Dec 4 (IANS) Insects play a very important role in cleaning up cities and they compete with other pests like rats and pigeons in their endeavour, a study has said. Scientists sampled arthropods - such as...
Read more on Business Balla
 
School headmaster shot dead in Pakistan
Islamabad, Dec 4 (IANS) Unidentified gunmen Thursday killed the headmaster of a private school in Pakistan's Balochistan province. Police officials said the armed men opened fire at the vehicle of Zahid Ali,...
Read more on Politics Balla
 
Four more bodies recovered from sunken South Korean ship
Seoul, Dec 4 (IANS) Four more bodies were recovered Thursday from a sunken South Korean fishing ship in the Bering Sea, the foreign ministry here said. This increased the toll to 16, including six South Koreans and 10...
Read more on Politics Balla
 
Lesbian couple asked to desist in London restaurant
London, Dec 4 (IANS) A lesbian couple in a London restaurant was asked to desist by a staff member, who asked them to "stop what you are doing". Lydia Cawson, 29, said that she and her girlfriend were asked by a staff...
Read more on Politics Balla
 
Oxford Dictionaries to add 1,000 new words
London, Dec 4 (IANS) 'Mamil' (middle-aged man in Lycra), 'silvertail' (a person who is socially prominent or who displays social aspirations) and 'crony capitalism' are among the 1,000 new words to be added to...
Read more on Celebrity Balla
 
Oceans play key role in global 'warming hiatus'
London, Dec 4 (IANS) Increased heat uptake across three oceans - North Atlantic, the Southern Ocean and Equatorial Pacific Ocean - is the likely cause of the 'warming hiatus' -- the current decade-long slowdown in...
Read more on Politics Balla
 
Novel imaging to identify if TB drugs are working
Washington, Dec 4 (IANS) Tuberculosis patients who are not cured of the infection can develop multi-drug resistant TB and have to take as many as six drugs for two years. Now, researchers at University of Pittsburgh...
Read more on Business Balla
 
PM makes first appointment to High Court of Australia
Canberra, Dec 4 (IANS) Prime Minister Tony Abbott's government Thursday appointed former Victorian Supreme Court judge Geoffrey Nettle as the next Justice of the High Court of Australia. Attorney General George...
Read more on Politics Balla
 
18 suspected militants killed in Pakistan airstrikes
Islamabad, Dec 4 (IANS) At least 18 suspected militants were killed Thursday in airstrikes conducted by Pakistan Air Force fighter jets in North Waziristan. According to officials, the airstrikes were conducted in...
Read more on Politics Balla