360° Coverage : BPA in plastic bottles impairs brain development

1 Updates
BPA in plastic bottles impairs brain development
Photo Credit: Pool, Getty Images

BPA in plastic bottles impairs brain development

Feb 26 2013, 10:58am CST | by

Washington, Feb 26 (IANS) Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

Washington, Feb 26 — Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new...

Filed under: news

YouTube Videos

 
 
 

1 year ago

BPA in plastic bottles impairs brain development

Feb 26 2013, 10:58am CST | by

Washington, Feb 26 (IANS) Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

Washington, Feb 26 — Bisphenol A (BPA), a compound present in plastics and resins, may suppress a gene vital to nerve cell function and impair the growth of the central nervous system, says a new study.

The chemical can be ingested if it seeps into the contents of food and beverage containers, according to medical researchers from Duke University.

"Our study found that BPA may impair the development of the central nervous system and raises the question as to whether exposure could predispose animals and humans to neuro-developmental disorders," said Wolfgang Liedtke, associate professor of medicine, neurology and neurobiology at Duke, who led the study.

BPA, a molecule that mimics estrogen and interferes with the body's endocrine system, can be found in a wide variety of manufactured products, including thermal printer paper, some plastic water bottles and the lining of metal cans, the journal Proceedings of the National Academy of Sciences reports.

Research in animals has raised concerns that exposure to BPA may cause health problems such as behavioural issues, endocrine and reproductive disorders, obesity, cancer and immune system disorders, according to a Duke statement.

Some studies suggest that infants and young children may be the most vulnerable to the effects of BPA, which led the US Food and Drug Administration to ban the use of the chemical in baby bottles and cups in July 2012.

While BPA has been shown to affect the developing nervous system, little is understood as to how this occurs. The research team developed a series of experiments in rodent and human nerve cells to learn how BPA induces changes that disrupt gene regulation.

Exposing neurons to minute amounts of BPA alters the chloride levels inside the cells by somehow shutting down the KCC2 gene, which makes the KCC2 protein, thereby delaying the removal of chloride from neurons.

MECP2, another protein important for normal brain function, was found to be a possible culprit behind this change. When exposed to BPA, MECP2 is more abundant and binds to the KCC2 gene at a higher rate, which might help to shut it down. This could trigger problems in the developing brain due to a delay in chloride removal.

"Our findings improve our understanding of how environmental exposure to BPA can affect the regulation of the KCC2 gene," Liedtke said.

IANS

Source: IANS

 

Don't miss ...

 

<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

blog comments powered by Disqus

Latest stories

27-Inch iMac Teardown Shows Similar Components to the Previous Version
27-Inch iMac Teardown Shows Similar Components to the Previous Version
The 27-inch Retina iMac possess identical internal construction of the previous generation model
 
 
Apple Aiming For Bigger Sales With The iPad Mini
Apple Aiming For Bigger Sales With The iPad Mini
The company isn’t only trying to sell the cheaper iPad after all
 
 
HomeKit Likely To See Release In 2015
HomeKit Likely To See Release In 2015
So far Apple has been silent about their smart home platform
 
 
Apple Pulls Bose Headphones
Apple Pulls Bose Headphones
The company quietly moved Bose headphones from its stores
 
 
 

Latest from the Network

Bush shoe-tossing painting hits record at Doha auction
Doha, Oct 15 (IANS/EFE) A controversial painting by Iranian artist Mahmud Obaidi, depicting an Iraqi journalist throwing shoe in 2008 at then US president George W. Bush, was sold for $62,500 at a Sotheby's auction in...
Read more on Celebrity Balla
 
US offers $45 mn bounty for eight terror leaders
Washington, Oct 15 (IANS) The US said Tuesday it is offering rewards totalling up to 45 million dollars for information on eight key leaders of the Al Qaeda in the Arabian Peninsula (AQAP) terrorist organisation. The...
Read more on Politics Balla
 
UNSC extends peacekeeping mission's term in Abyei
United Nations, Oct 15 (IANS) The UN Security Council (UNSC) has renewed the mandate of the UN peacekeeping mission in the Abyei border region between Sudan and South Sudan. In an unanimously adopted resolution, the...
Read more on Politics Balla
 
Ebola cases in West Africa could reach 10,000 per week: WHO
Geneva, Oct 15 (IANS) The World Health Organisation (WHO) has warned that the Ebola epidemic in West Africa could reach 5,000 to 10,000 cases per week by the first week of December. "Quite frankly, ladies and...
Read more on Business Balla
 
Turkey, Singapore sign strategic partnership agreement
Ankara, Oct 15 (IANS) Turkey and Singapore have signed a strategic partnership agreement to boost economic, political and cultural cooperation, as well as security collaboration, during the official visit of...
Read more on Politics Balla
 
Christina Aguilera is returning to 'The Voice' USA
Christina Aguilera will return to 'The Voice' USA next year. The 'Your Body' hitmaker, who previously shared a rotating spot on the judging panel with Shakira, has been replaced by Gwen Stefani this season as she is...
Read more on Celebrity Balla
 
Kesha's music producer hits back
Kesha is being countersued by her record company boss, Dr. Luke. The 41-year-old music producer, who runs Kemosabe Records, claims the 27-year-old 'Tik Tok' singer is a liar and is trying to extort him after she accused...
Read more on Celebrity Balla
 
Jason Derulo won't get back together with Jordin Sparks
Jason Derulo insists his split from Jordin Sparks is permanent. The 'Talk Dirty' hitmaker, who recently ended his relationship with the 'No Air' singer after three years of dating, has ruled out getting back together...
Read more on Celebrity Balla
 
Josh Groban feels 'very lucky' to be dating Kat Dennings
Josh Groban feels ''very lucky'' to be dating Kat Dennings. The 'Brave' hitmaker was very nervous before singing in front of the '2 Broke Girls' actress for the first time at the Carousel of Hope Ball in Beverly Hills,...
Read more on Celebrity Balla
 
Australian Richard Flanagan wins 2014 Man Booker prize
London, Oct 15 (IANS) The first Man Booker prize to allow American nominees was Tuesday night won by an Australian, with Richard Flanagan triumphing for a novel of love and war that tells the harrowing stories of...
Read more on Celebrity Balla