8 Updates

Drug shows promise in busting Hepatitis C virus

Feb 19 2013, 5:26am CST | by

Washington, Feb 19 (IANS) Hepatitis C virus (HCV) infection affects about 4.1 million people in the United States alone and is the primary cause of liver cirrhosis and liver cancer. Current therapy against the infection is not particularly effective.

Washington, Feb 19 — Hepatitis C virus (HCV) infection affects about 4.1 million people in the United States alone and is the primary cause of liver cirrhosis and liver cancer. Current therapy...

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Update
8

7 hours ago

Burbank Man Latest Person To Sue Costco After Allegedly Contracting Hepatitis A From Frozen Berries

Source: CBS Los Angeles  |   Jun 19 2013, 9:42pm CDT

BURBANK (CBSLA.com) —A 52-year-old man has become the latest person to sue Costco after allegedly contracting hepatitis A from frozen berries he purchased at the warehouse chain’s Burbank store. Attorney Ron Simon s ...

Continue reading on: CBS Los Angeles  More like this

 
Update
7

12 hours ago

Hepatitis C victim described organ failure in deposition before his death

Source: Las Vegas Review-Journal | LVRJ.com  |   Jun 19 2013, 4:52pm CDT

Prosecutors this morning began playing for a jury the videotaped deposition of hepatitis C outbreak victim Rodolfo Meana that was taken several weeks before his 2012 death. Meana, 77, flew to the Philippines a week after the March 20, 20 ...

Continue reading on: Las Vegas Review-Journal | LVRJ.com  More like this

 
Update
5


Quote:
"As Hepatitis B and C are the main causes of liver cancer, childhood vaccination against hepatitis B may reduce the risk of liver cancer in the future. In case of patients with cirrhosis alcohol consumption is to be avoided."


Source: Times of India

 
Update
4

13 hours ago

Hepatitis A virus infections associated with berry and pomegranate mix

Source: Virology Blog  |   Jun 19 2013, 3:25pm CDT

Hepatitis A virus is a member of the picornavirus family, which also contains poliovirus and rhinovirus. The virion is a naked, icosahedral particle containing a single strand of positive-sense RNA. Infection is typically ac ...

Continue reading on: Virology Blog  More like this

 
Update
2

14 hours ago

PharmaPoint: Hepatitis C Virus - China Drug Forecast and Market Analysis

Source: PR Newswire  |   Jun 19 2013, 2:49pm CDT

NEW YORK, June 19, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Summary GlobalData has released its new Country report, "PharmaPoint: Hepatitis C Virus - China Drug Forec ...

Continue reading on: PR Newswire  More like this

 
Update
1

14 hours ago

Simon & Luke and Gomez Iagmin File Fifth Hepatitis Lawsuit Against Townsend Farms and Costco in Los Angeles

Source: iStockAnalyst  |   Jun 19 2013, 2:35pm CDT

Every trading day, be ready to attack the market instead of reacting to the market. You will know where the key technical resistance and support levels are and what the market is likely to do next. iStock will arm you with a tar ...

Continue reading on: iStockAnalyst  More like this

 
 

17 weeks ago

Drug shows promise in busting Hepatitis C virus

Feb 19 2013, 5:26am CST | by

Washington, Feb 19 (IANS) Hepatitis C virus (HCV) infection affects about 4.1 million people in the United States alone and is the primary cause of liver cirrhosis and liver cancer. Current therapy against the infection is not particularly effective.

Washington, Feb 19 — Hepatitis C virus (HCV) infection affects about 4.1 million people in the United States alone and is the primary cause of liver cirrhosis and liver cancer. Current therapy against the infection is not particularly effective.

Daclatasvir, a direct acting antiviral (DAA) agent, targets one of the HCV proteins NS5A and causes the fastest viral decline, within 12 hours of treatment ever seen with anti-HCV drugs.

An interdisciplinary effort by mathematical modellers, clinicians and molecular virologists has revealed that daclatasvir has two main modes of action against HCV and also yields a new, more accurate estimate of the HCV half-life, the journal Proceedings of the National Academy of Sciences reports.

"Ultimately, our study will help design better DAA drug cocktails to treat HCV," said Loyola University Health System (LUHS) and Stritch School of Medicine (SSOM) mathematical modeller Harel Dahari, who co-led the study.

Dahari is one of five members of the Division of Hepatology at Loyola headed by Scott Cotler, who authored the study with Thomas Layden, HCV virologist Susan L. Uprichard and her doctoral graduate student Natasha Sansone, according to a Loyola statement.

"Daclatasvir not only blocks the synthesis of the viral RNA within infected cells but also secretion of infectious virus from the cells," said Dahari.

This prediction was confirmed in Uprichard's lab using cultured liver cells that support the entire life cycle of HCV infection.

IANS

Source: IANS

 

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<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

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