360° Coverage : Scientists switch off ability to sense cold

1 Updates
Scientists switch off ability to sense cold
Photo Credit: Leigh Vogel, Getty Images

Scientists switch off ability to sense cold

Feb 13 2013, 5:47am CST | by

Washington, Feb 13 (IANS) A group of American scientists have successfully managed to selectively shut off in mice the ability to feel cold while leaving the sensation of touch and heat intact.

Washington, Feb 13 — A group of American scientists have successfully managed to selectively shut off in mice the ability to feel cold while leaving the sensation of touch and heat intact....

Filed under: news

YouTube Videos

 
 
 

1 year ago

Scientists switch off ability to sense cold

Feb 13 2013, 5:47am CST | by

Washington, Feb 13 (IANS) A group of American scientists have successfully managed to selectively shut off in mice the ability to feel cold while leaving the sensation of touch and heat intact.

Washington, Feb 13 — A group of American scientists have successfully managed to selectively shut off in mice the ability to feel cold while leaving the sensation of touch and heat intact.

Neuroscientists at USC Dornsife College of Letters, Arts and Sciences have isolated chills at a cellular level, identifying the sensory network of neurons in the skin that relays the sensation of cold.

David McKemy, associate professor of neurobiology in the USC Dornsife College of Letters, Arts and Sciences, and his team managed to selectively shut off the ability to sense cold in mice while still leaving them able to sense heat and touch.

In prior work, McKemy discovered a link between the experience of cold and a protein known as TRPM8 (pronounced trip-em-ate), which a sensor of cold temperatures in neurons in the skin, as well as a receptor for menthol, the cooling component of mint.

Now, in a paper appearing in the Journal of Neuroscience Feb 13, McKemy and his co-investigators have isolated and ablated the neurons that express TRPM8, giving them the ability to test the function of these cells specifically.

The researchers found that mice depleted of TRPM8 neurons could not feel cold, but still responded to heat, reports Science Daily.

"One of our goals is to pave the way for medications that address the pain directly, in a way that does not leave patients completely numb," said McKermy.

IANS

Source: IANS

 

Don't miss ...

 

<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

blog comments powered by Disqus

Latest stories

Europe's Galileo satellites launched into wrong orbit
Paris, Aug 23 (IANS) European satellite launch company Arianespace announced Saturday that the two satellites of Europe's Galileo satellite navigation system launched Friday from the European spaceport in French Guiana were delivered into the wrong orbit.
 
 
White dwarf stars formed mysterious supernova
London, Aug 23 (IANS) Supernova 2014J is 11 million light years away from earth and was only seen by chance at the University of London Observatory this year.
 
 
Universe's earliest stars were monstrous: Study
Tokyo, Aug 23 (IANS) Little is known about the universe's earliest stars but if we believe astronomers, they might have been hundreds of times more massive than the sun.
 
 
Killer fungus that grows on trees
New York, Aug 23 (IANS) A teenaged girl has helped scientists discover that a deadly fungus that generally attacks HIV/AIDS patients grows on trees.
 
 
 

Latest from the Network

Force India struggle in wet Belgian GP qualifying
Spa-Francorchamps (Belgium), Aug 23 (IANS) Force India drivers Sergio Perez and Nico Hulkenberg had a difficult outing in the Belgian Grand Prix qualifying Saturday and will start Sunday's race 13th and 18th....
Read more on Sport Balla
 
Simon Pegg finds watching himself hard
Simon Pegg sometimes finds it ''hard'' to watch his own movies. The 44-year-old actor - who has five-year-old daughter Matilda with wife Maureen - is very ''proud'' of his work but doesn't enjoying viewing them back as...
Read more on Movie Balla
 
Indian cueists bag Asian title
Karachi, Aug 23 (IANS) India A, consisting of Kamal Chawla, Faisal Khan and Dharmender Lilly, won the Gold medal in the Asian Snooker Team championship here Saturday, defeating Pakistan A 3-1 in the final. The Indian...
Read more on Sport Balla
 
Sri Lanka, Pakistan 2nd ODI shifted to Hambantota
Colombo, Aug 23 (IANS) The second One-Day International (ODI) between Sri Lanka and Pakistan was Saturday moved up to Aug 26 and the venue shifted to Hambantota after heavy rainfall here left the Premadasa Stadium...
Read more on Sport Balla
 
Stacy Keibler gives birth to daughter
Los Angeles, Aug 23 (IANS) Former wrestler-turned-actress Stacy Keibler has welcomed a girl child. The 34-year-old and her husband, Jared Pobre, welcomed their daughter, Ava Grace Pobre, into the world Wednesday, she...
Read more on Celebrity Balla
 
Britain mulls steps to combat extremism
London, Aug 23 (IANS) To discourage extremist elements originating from Britain, Home Secretary Theresa May has plans to bring in new laws that may strip Britons fighting in Syria and Iraq of their citizenship. May is...
Read more on Politics Balla
 
Europe's Galileo satellites launched into wrong orbit
Paris, Aug 23 (IANS) European satellite launch company Arianespace announced Saturday that the two satellites of Europe's Galileo satellite navigation system launched Friday from the European spaceport in French Guiana...
Read more on Apple Balla
 
Indian man commits suicide in UAE
Dubai, Aug 23 (IANS) A 24-year-old Indian man was found dead Saturday at his home in the United Arab Emirates (UAE), a media report said. The man, identified by his initials R.M., committed suicide by hanging himself...
Read more on Politics Balla
 
Boy killed in Israeli airstrike on Gaza
Gaza, Aug 23 (IANS) An eight-year-old boy was killed and three others wounded in a fresh Israeli airstrike Saturday afternoon on a house in the central Gaza Strip, medics said. Ashraf al-Qedra, the health ministry...
Read more on Politics Balla
 
Toll in Japan mudslides hits 49
Tokyo, Aug 23 (IANS) The toll in deadly landslides in the Japanese city of Hiroshima rose to 49 Saturday, while 41 people remained missing. About 2,800 rescuers continued their efforts in searching for survivors three...
Read more on Politics Balla