Researchers cure type 1 diabetes in dogs

Madrid, Feb 8 (IANS) Researchers cured type 1 diabetes among dogs by using only a single session of gene therapy, potentially paving the way for treatment of diabetic patients.

Feb 8 2013, 3:34am CST | by

Madrid, Feb 8 — Researchers cured type 1 diabetes among dogs by using only a single session of gene therapy, potentially paving the way for treatment of diabetic patients.

Fatima Bosch, from the Universitat Autonoma deBarcelona (UAB), who led the study and obtained excellent results for the first time, points out: "This study is the first to demonstrate a long-term cure for diabetes in a large animal model using gene therapy."

Type 1 diabetes, also called juvenile diabetes or insulin-dependent diabetes, is a disorder of the body's immune system.

The finding showed that after this treatment, the dogs recovered their health and no longer showed symptoms of the disease. In some cases, monitoring for over four years also bore out the same results, the journal Diabetes reports.

The therapy is minimally invasive and consists of a single session of various injections in the animal's rear legs using simple needles that are commonly used in cosmetic treatments, according to an UAB statement.

These injections introduce gene therapy vectors, with a dual objective: to express the insulin gene, on the one hand, and that of glucokinase, on the other.

Glucokinase is an enzyme that regulates the uptake of glucose from the blood.

When both genes act simultaneously they function as a "glucose sensor", which automatically regulates the uptake of glucose from the blood, thus reducing diabetic hyperglycemia (the excess of blood sugar associated with the disease).

IANS

Source: IANS

 
 
 

<a href="/latest_stories/all/all/8" rel="author">Luigi Lugmayr</a>
Luigi is the founding Chief Editor of I4U News and brings over 15 years experience in the technology field to the ever evolving and exciting world of gadgets. He started I4U News back in 2000 and evolved it into vibrant technology magazine.
Luigi can be contacted directly at ml@i4u.com. Luigi posts regularly on LuigiMe.com about his experience running I4U.

 

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